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[2] Hepatic Concerns In rodent studies using doses 5-10 times higher than proposed therapeutic levels, approximately 8-12% of subjects showed elevated liver enzymes (ALT increases of 2-3 times upper normal limits) after 4-6 weeks of daily administration
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however, the significance of the modification is yet to be explored (Mustafa et al ., 2009) (Figure 2B)
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